it is important to remember to begin a blues tune with a one measure count , a measure of rhythm then the others join in. . the lead player can then begin.
when playing lead don't just play scales, leave a little space . hold a note hear and there. keep in mind the call and response . think about playing phrases such as something your wife might say . i.e. Honey take the garbage out and close the door behind you. you can put notes to that in the same manner you might speak it. then think about how you might respond to that request using the notes of the pentatonic scale.
Don't play like bluegrass !